Description

2-Chloro-6-Trifluoromethoxy-Benzoic Acid is a high-purity, multi-functional benzoic acid derivative characterized by its chloro and trifluoromethoxy substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals, where its aromatic core and halogenated groups modify material properties.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-6-Trifluoromethoxy-Benzoic Acid
CAS No.	1261617-84-8
Molecular Formula	C8H4ClF3O3
Molecular Weight	240.56 g/mol
Synonyms	2-Chloro-6-(trifluoromethoxy)benzoic acid; Benzoic acid, 2-chloro-6-(trifluoromethoxy)-; 6-Chloro-2-(trifluoromethoxy)benzoic acid; 2-Chloro-α,α,α-trifluoro-6-methoxybenzoic acid (ambiguous); 2-Chloro-6-trifluoromethoxybenzoic acid; 2-Cl-6-OCF3-Benzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-Trifluoromethoxy-Benzoic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure compliance with exacting purity standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.