Description

Benzamide, 2-Hydroxy-3-(Trifluoromethoxy)- CAS NO 1261610-87-0 is a specialized trifluoromethoxy-substituted benzamide derivative, a high-value chemical intermediate prized for its unique structural motif. This compound matters for its role in facilitating the synthesis of advanced molecules, particularly in the pharmaceutical and agrochemical sectors, where the trifluoromethoxy group is known to enhance metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, including kinase inhibitors, herbicides, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting protein kinases and other enzymes.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, leveraging the bioactivity of the trifluoromethoxy group.
• Material Science: Serves as a precursor for advanced polymers and liquid crystals where specific fluorine-containing aromatic units are required.
• Chemical Synthesis: Employed in organic synthesis as a versatile intermediate for introducing the 2-hydroxy-3-(trifluoromethoxy)benzoyl moiety into more complex structures.
• Life Science Reagents: Utilized in the preparation of biochemical probes and tool compounds for biological research and assay development.

Basic Information

Product Name	Benzamide, 2-Hydroxy-3-(Trifluoromethoxy)-
CAS No.	1261610-87-0
Molecular Formula	C8H6F3NO3
Molecular Weight	221.14 g/mol
Synonyms	2-Hydroxy-3-(trifluoromethoxy)benzamide; 3-(Trifluoromethoxy)salicylamide; 2-Carbamoyl-6-(trifluoromethoxy)phenol; Salicylamide, 3-(trifluoromethoxy)-; 2-Hydroxy-3-(trifluoromethoxy)benzoic acid amide; 1261610-87-0; Benzamide, 2-hydroxy-3-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our Benzamide, 2-Hydroxy-3-(Trifluoromethoxy)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.