Description

8-Iodoquinolin-2-Ol is a halogenated quinoline derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique iodine substituent enables crucial cross-coupling reactions. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel active compounds and ligands.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in antimicrobial, anticancer, and anti-inflammatory research pipelines.
• Agrochemical Synthesis: Used in the development of next-generation fungicides, herbicides, and plant growth regulators.
• Catalyst & Ligand Development: Serves as a building block for creating sophisticated ligands used in transition metal catalysis for fine chemical production.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings.

Basic Information

Product Name	8-Iodoquinolin-2-Ol
CAS No.	1261578-65-7
Molecular Formula	C9H6INO
Molecular Weight	271.06 g/mol
Synonyms	8-Iodo-2-hydroxyquinoline; 2-Hydroxy-8-iodoquinoline; 8-Iodoquinolin-2-ol; Quinolin-2-ol, 8-iodo-; 8-Iodo-2-quinolinol
EINECS	Contact for details

Quality Control

Our 8-Iodoquinolin-2-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.