Description

2-Chloro-5-(Difluoromethyl)Aniline is a versatile halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of chlorine and difluoromethyl groups on the aromatic ring, which are key for modulating the electronic and steric properties of target molecules. This intermediate is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Acts as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Serves as an intermediate for creating complex, high-performance dyes and pigments with specific color fastness and stability properties.
• Polymer Modification: Employed to introduce functional aniline groups into polymer chains, altering material properties like conductivity or adhesion.
• Research & Development: Essential for academic and industrial research in medicinal chemistry and material science for exploring new molecular entities.

Basic Information

Product Name	2-Chloro-5-(Difluoromethyl)Aniline
CAS No.	1261567-27-4
Molecular Formula	C7H6ClF2N
Molecular Weight	177.58 g/mol
Synonyms	2-Chloro-5-(difluoromethyl)benzenamine; 5-Amino-2-chlorobenzylidene difluoride; Benzenamine, 2-chloro-5-(difluoromethyl)-; 2-Chloro-α,α-difluoro-m-toluidine; 2-Chloro-5-difluoromethylphenylamine; 2-Chloro-5-(difluoromethyl)phenylamine; 2-Chloro-5-(difluoromethyl)aniline (primary name)
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Difluoromethyl)Aniline is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.