Description

4-Methoxy-3-(Trifluoromethoxy)Phenylacetic Acid, 97% is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of methoxy and trifluoromethoxy substituents, which are critical for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for advanced electronic and display materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and amide bond formations to introduce a functionalized phenylacetic acid moiety.
• Chemical Biology & Proteomics: Can be utilized as a linker or a tagged scaffold in the design of chemical probes and bio-conjugation reagents.

Basic Information

Product Name	4-Methoxy-3-(Trifluoromethoxy)Phenylacetic Acid, 97%
CAS No.	1261557-46-3
Molecular Formula	C10H9F3O4
Molecular Weight	250.17 g/mol
Synonyms	[4-Methoxy-3-(trifluoromethoxy)phenyl]acetic acid; 2-[4-Methoxy-3-(trifluoromethoxy)phenyl]acetic acid; 3-(Trifluoromethoxy)-4-methoxyphenylacetic acid; 4-Methoxy-3-trifluoromethoxyphenylacetic acid; (4-Methoxy-3-(trifluoromethoxy)phenyl)acetic acid; 1261557-46-3; Phenylacetic acid, 4-methoxy-3-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-(Trifluoromethoxy)Phenylacetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure the specified purity and identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with our rigorous specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.