Description

2-Amino-6-(Trifluoromethoxy)Phenol is a specialized aromatic compound featuring both an amino and a trifluoromethoxy substituent, making it a valuable building block in advanced organic synthesis. Its unique structure offers significant potential for modulating the physicochemical properties of target molecules, particularly in enhancing metabolic stability and lipophilicity. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring fluorine-containing motifs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, where its aromatic core and substituents contribute to desired electronic and optical properties.
• Complex Ligand & Catalyst Development: Employed in organometallic chemistry for creating specialized ligands that can modulate catalyst performance in asymmetric synthesis.
• Dye & Pigment Research: Acts as an intermediate in the development of specialized dyes and functional pigments with tailored colorfastness and application properties.
• Academic & Industrial R&D: A versatile reagent for methodological studies and exploratory chemistry in both university laboratories and corporate R&D centers.

Basic Information

Item	Details
Product Name	2-Amino-6-(Trifluoromethoxy)Phenol
CAS No.	1261524-09-7
Molecular Formula	C7H6F3NO2
Molecular Weight	193.12 g/mol
Synonyms	6-Amino-2-(trifluoromethoxy)phenol; 2-Hydroxy-3-(trifluoromethoxy)aniline; 2-Amino-6-(trifluoromethoxy)benzenol; 3-Amino-2-hydroxybenzotrifluoride (related); 2-(Trifluoromethoxy)-6-aminophenol; Phenol, 2-amino-6-(trifluoromethoxy)-; 6-(Trifluoromethoxy)-2-aminophenol
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-6-(Trifluoromethoxy)Phenol is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.