Description

2-Chloro-3-(Difluoromethyl)Aniline is a versatile halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both chloro and difluoromethyl substituents, enabling precise modulation of electronic and steric properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance bioavailability and environmental stability.
• Material Science: Used in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for creating complex, high-performance organic dyes and pigments with specific light-fastness properties.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl and heterocyclic structures.
• Research & Development: Serves as a standard or reagent in academic and industrial R&D for exploring new synthetic methodologies and structure-activity relationships.

Basic Information

Product Name	2-Chloro-3-(Difluoromethyl)Aniline
CAS No.	1261499-71-1
Molecular Formula	C7H6ClF2N
Molecular Weight	177.58 g/mol
Synonyms	2-Chloro-3-(difluoromethyl)benzenamine; 3-Amino-2-chlorobenzylidene difluoride; 2-Chloro-α,α-difluoro-m-toluidine; Benzenamine, 2-chloro-3-(difluoromethyl)-; 2-Chloro-3-difluoromethylphenylamine; 2-Chloro-3-(difluoromethyl)phenylamine; 3-(Difluoromethyl)-2-chloroaniline
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(Difluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.