Description

8-(Trifluoromethyl)Quinolin-3-Ol is a high-purity fluorinated quinoline derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in the unique electronic and steric properties imparted by the trifluoromethyl group, which is critical for modulating the biological activity and physicochemical characteristics of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly for targets in oncology, central nervous system (CNS) disorders, and anti-infective therapies.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides, where the CF3 group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry, including cross-coupling and heterocyclic chemistry.

Basic Information

Product Name	8-(Trifluoromethyl)Quinolin-3-Ol
CAS No.	1261489-93-3
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	3-Hydroxy-8-(trifluoromethyl)quinoline; 8-(Trifluoromethyl)-3-quinolinol; 8-Trifluoromethylquinolin-3-ol; Quinolin-3-ol, 8-(trifluoromethyl)-; 3-Quinolinol, 8-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 8-(Trifluoromethyl)Quinolin-3-Ol is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (HPLC), with detailed impurity profiling available. Certificates of Analysis (COA) are provided with each shipment, and we support compliance with relevant regulatory frameworks for our customers' target markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.