Description

5-Amino-2-(Trifluoromethoxy)Benzamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethoxy-substituted benzamide structure. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific fluorine chemistry for enhanced metabolic stability and bioavailability. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethoxy group contributes to biological activity.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that require fluorine-containing aromatic units.
• Organic Synthesis: Utilized in academic and industrial R&D for constructing complex molecules via its reactive amino and amide functional groups.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the effects of the trifluoromethoxy substituent on chemical reactivity and physical properties.

Basic Information

Product Name	5-Amino-2-(Trifluoromethoxy)Benzamide
CAS No.	1261471-58-2
Molecular Formula	C8H7F3N2O2
Molecular Weight	220.15 g/mol
Synonyms	2-Amino-5-carbamoyl-1-(trifluoromethoxy)benzene; 2-Trifluoromethoxy-5-aminobenzamide; 5-Amino-2-(trifluoromethoxy)benzamide; Benzamide, 5-amino-2-(trifluoromethoxy)-; 5-Amino-α,α,α-trifluoro-o-anisamide
EINECS	Contact for details

Quality Control

Our 5-Amino-2-(Trifluoromethoxy)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical and advanced chemical synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring supply reliability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.