Description

(Rac)-trans-1-tert-Butyl 3-Methyl 4-(1,5-Naphthyridin-3-Yl)Pyrrolidine-1,3-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is critical for medicinal chemists seeking to explore and optimize the biological activity of novel therapeutic candidates, particularly those targeting complex disease pathways. Its primary value lies in enabling the synthesis of sophisticated molecular architectures, making it essential for pharmaceutical companies, contract research organizations (CROs), and academic laboratories focused on oncology, neurology, and infectious disease research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential active pharmaceutical ingredients (APIs) for preclinical and clinical studies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new drug candidates with optimized potency and selectivity.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) against novel biological targets.
• Process Chemistry Development: Acts as a reference standard or starting material for scaling up and optimizing synthetic routes under Good Manufacturing Practice (GMP) guidelines.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic methodologies and reaction mechanisms involving complex heterocycles.

Basic Information

Product Name	(Rac)-trans-1-tert-Butyl 3-Methyl 4-(1,5-Naphthyridin-3-Yl)Pyrrolidine-1,3-Dicarboxylate
CAS No.	1261365-91-6
Molecular Formula	C20H25N3O4
Molecular Weight	371.44 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-methyl 4-(1,5-naphthyridin-3-yl)pyrrolidine-1,3-dicarboxylate; 1-Boc-3-methyl 4-(1,5-naphthyridin-3-yl)pyrrolidine-1,3-dicarboxylate; tert-Butyl 3-methyl 4-(1,5-naphthyridin-3-yl)pyrrolidine-1,3-dicarboxylate; 4-(1,5-Naphthyridin-3-yl)pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl 3-methyl ester; (Rac)-trans-1-Boc-3-Me 4-(1,5-Naphthyridin-3-yl)pyrrolidine-1,3-dicarboxylate; 1261365-91-6; 1,5-Naphthyridine-3-yl pyrrolidine derivative
EINECS	Contact for details

Quality Control

Our production of (Rac)-trans-1-tert-Butyl 3-Methyl 4-(1,5-Naphthyridin-3-Yl)Pyrrolidine-1,3-Dicarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment, supporting compliance with internal quality standards and regulatory readiness for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.