Description

4-Iodo-3-Methoxy-1,5-Naphthyridine is a high-value, halogenated naphthyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring both iodine and methoxy substituents, makes it an indispensable intermediate for constructing complex heterocyclic frameworks. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a building block for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Cross-Coupling Reactions: The iodine atom provides an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse chemical libraries.
• Chemical Biology: Utilized as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Academic & Contract Research: Serves as a specialized reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	4-Iodo-3-Methoxy-1,5-Naphthyridine
CAS No.	1261365-88-1
Molecular Formula	C9H7IN2O
Molecular Weight	286.07 g/mol
Synonyms	3-Methoxy-4-iodo-1,5-naphthyridine; 4-Iodo-3-methoxy-1,5-naphthyridine; 1,5-Naphthyridine, 4-iodo-3-methoxy-; 1261365-88-1
EINECS	Contact for details

Quality Control

Every batch of 4-Iodo-3-Methoxy-1,5-Naphthyridine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.