Description

1-(4-Chloro-6-Methyl-Pyrimidin-2-Yl)-Pyrrolidin-3-Ol is a high-purity, functionalized pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific heterocyclic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A versatile synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the pyrimidine core provides essential bioactivity.
• Chemical Research: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials and ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production and scale-up projects.

Basic Information

Product Name	1-(4-Chloro-6-Methyl-Pyrimidin-2-Yl)-Pyrrolidin-3-Ol
CAS No.	1261234-29-0
Molecular Formula	C9H12ClN3O
Molecular Weight	213.66 g/mol
Synonyms	3-Pyrrolidinol, 1-(4-chloro-6-methyl-2-pyrimidinyl)-; 1-(4-Chloro-6-methylpyrimidin-2-yl)pyrrolidin-3-ol; 2-(3-Hydroxypyrrolidin-1-yl)-4-chloro-6-methylpyrimidine; 4-Chloro-6-methyl-2-(3-pyrrolidinyloxy)pyrimidine; Pyrrolidin-3-ol, 1-(4-chloro-6-methyl-2-pyrimidinyl)-; (RS)-1-(4-Chloro-6-methylpyrimidin-2-yl)pyrrolidin-3-ol
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-6-Methyl-Pyrimidin-2-Yl)-Pyrrolidin-3-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.