Description

2-(4-Chloro-Benzyloxymethyl)-Pyrrolidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1261232-79-4. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a key building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical producers seeking reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacologically active molecules.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up API manufacturing processes under GMP conditions.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, agrochemicals, and other complex organic compounds requiring a pyrrolidine scaffold.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for the pharmaceutical and biotechnology industries.

Basic Information

Product Name	2-(4-Chloro-Benzyloxymethyl)-Pyrrolidine Hydrochloride
CAS No.	1261232-79-4
Molecular Formula	C12H16ClNO • HCl
Molecular Weight	262.17 g/mol
Synonyms	2-[(4-Chlorobenzyl)oxymethyl]pyrrolidine hydrochloride; 1-(4-Chlorobenzyloxymethyl)pyrrolidine hydrochloride; Pyrrolidine, 2-[(4-chlorophenyl)methoxy]methyl]-, hydrochloride (1:1); (4-Chloro-benzyloxymethyl)-pyrrolidine HCl; 1261232-79-4
EINECS	Contact for details

Quality Control

Our 2-(4-Chloro-Benzyloxymethyl)-Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected by the pharmaceutical industry for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.