Description

6-Bromo-3-Iodoquinolin-4-Ol CAS NO 1260886-58-5 is a halogenated quinoline derivative, a versatile and highly functionalized heterocyclic building block. Its unique structure, featuring both bromine and iodine substituents, makes it a critical intermediate for constructing complex molecules in advanced research and development. This compound is essential for medicinal chemists and material scientists working in pharmaceutical discovery, agrochemical development, and organic electronics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobial agents, and other biologically active quinoline-based compounds.
• Agrochemical Research: Used in the creation of new pesticides and herbicides, where the halogenated quinoline core can contribute to specific modes of action and efficacy.
• Material Science: Acts as a building block for organic semiconductors, ligands for catalysis, and functional dyes due to its electron-rich aromatic system and halogen handles for further cross-coupling reactions.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) where the bromine and iodine atoms offer orthogonal reactivity for sequential functionalization.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for probing structure-activity relationships (SAR) in various applied research fields.

Basic Information

Product Name	6-Bromo-3-Iodoquinolin-4-Ol
CAS No.	1260886-58-5
Molecular Formula	C9H5BrINO
Molecular Weight	349.95 g/mol
Synonyms	4-Quinolinol, 6-bromo-3-iodo-; 6-Bromo-3-iodo-4-quinolinol; 6-Bromo-3-iodoquinolin-4-ol; 3-Iodo-6-bromoquinolin-4-ol; 4-Hydroxy-6-bromo-3-iodoquinoline; 6-Br-3-I-4-OH-Quinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Iodoquinolin-4-Ol is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.