Description

3-Fluoro-5-(Piperidin-3-Yl)Pyridine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel small-molecule therapies.
• API Development: Serves as a core scaffold for developing active pharmaceutical ingredients with potential antipsychotic or antidepressant activity.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying receptor interactions and signaling pathways.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client research programs.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API production.

Basic Information

Item	Details
Product Name	3-Fluoro-5-(Piperidin-3-Yl)Pyridine Dihydrochloride
CAS No.	1260864-37-6
Molecular Formula	C10H14Cl2FN2
Molecular Weight	249.14 g/mol
Synonyms	3-(5-Fluoropyridin-3-yl)piperidine dihydrochloride; 3-Piperidin-3-yl-5-fluoropyridine dihydrochloride; 5-Fluoro-3-(3-piperidyl)pyridine dihydrochloride; 3-(5-Fluoro-3-pyridinyl)piperidine dihydrochloride; 3-Fluoro-5-(3-piperidyl)pyridine hydrochloride (1:2); 1260864-37-6 (CAS)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Piperidin-3-Yl)Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97%), and impurity profiles is provided with every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.