Description

6-Allyl-4-Amino-2-(Trifluoromethyl)Quinoline-3-Carbonitrile is a high-value, multi-functional quinoline derivative featuring a reactive allyl group and a trifluoromethyl substituent. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, enabling the development of novel compounds with enhanced biological activity and physicochemical properties. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and material science industries seeking to incorporate its unique trifluoromethyl and cyano-functionalized quinoline scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, anti-cancer agents, and anti-inflammatory compounds.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Building Block: Employed in the creation of specialty chemicals, organic electronic materials, and functional dyes due to its conjugated quinoline system.
• Chemical Biology Probe: Serves as a scaffold for designing molecular probes to study biological pathways and enzyme functions.
• Organic Synthesis Reagent: Utilized in cyclization reactions, cross-coupling reactions, and as a substrate for further functionalization via its amino and allyl groups.

Basic Information

Product Name	6-Allyl-4-Amino-2-(Trifluoromethyl)Quinoline-3-Carbonitrile
CAS No.	1260863-08-8
Molecular Formula	C14H10F3N3
Molecular Weight	277.25 g/mol
Synonyms	4-Amino-6-allyl-2-(trifluoromethyl)quinoline-3-carbonitrile; 2-(Trifluoromethyl)-6-allyl-4-amino-3-cyanoquinoline; 6-Allyl-4-amino-2-trifluoromethyl-3-quinolinecarbonitrile; 3-Cyano-4-amino-6-allyl-2-trifluoromethylquinoline; 1260863-08-8; 4-Amino-6-allyl-2-(trifluoromethyl)-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 6-Allyl-4-Amino-2-(Trifluoromethyl)Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.