Description

1-(3-Fluoro-4-Methoxyphenyl)Cyclopropanamine Hydrochloride is a high-purity, fine chemical intermediate characterized by its unique cyclopropylamine structure substituted with a fluorinated methoxyphenyl group. This compound is of significant value in modern organic synthesis, particularly for constructing complex molecular architectures with enhanced biological activity and metabolic stability. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom and cyclopropane ring can improve efficacy and environmental profile.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or a functional handle for creating molecular probes and tool compounds to study biological pathways.
• Material Science Precursor: Potential use in synthesizing specialty polymers or advanced organic materials requiring specific fluorinated aromatic amines.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up projects under cGMP or non-GMP conditions.

Basic Information

Product Name	1-(3-Fluoro-4-Methoxyphenyl)Cyclopropanamine Hydrochloride
CAS No.	1260852-84-3
Molecular Formula	C10H13FNO • HCl
Molecular Weight	217.67 g/mol (Free base) / 254.13 g/mol (Hydrochloride salt)
Synonyms	1-(3-Fluoro-4-methoxyphenyl)cyclopropanamine HCl; 1-(3-Fluoro-4-methoxyphenyl)cyclopropan-1-amine hydrochloride; 3-Fluoro-4-methoxy-α-(cyclopropylamino)toluene hydrochloride; 1-Amino-1-(3-fluoro-4-methoxyphenyl)cyclopropane hydrochloride; (3-Fluoro-4-methoxyphenyl)cyclopropylamine hydrochloride; 1-Cyclopropyl-1-(3-fluoro-4-methoxyphenyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our production of 1-(3-Fluoro-4-Methoxyphenyl)Cyclopropanamine Hydrochloride adheres to stringent internal quality standards, ensuring batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and commercial projects with specifications tailored to meet cGMP, ICH Q7 guidelines, and client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.