Description

Ethyl 2-(3-Cyano-6-Fluoro-2-(trifluoromethyl)quinolin-4-yl)acetate is a high-value, multifunctional quinoline derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its molecular architecture, featuring a cyano group, fluorine, and trifluoromethyl substituents, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop new generations of herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold and fluorine atoms.
• Material Science: Serves as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge-transport materials, due to its conjugated system and electron-withdrawing groups.
• Chemical Synthesis: Employed as a versatile synthon in organic chemistry for constructing complex heterocyclic systems via cyclization, cross-coupling, and functional group transformation reactions.
• Fluorine Chemistry Studies: Acts as a model compound for studying the effects of fluorine and trifluoromethyl groups on molecular reactivity, stability, and physicochemical properties.

Basic Information

Item	Details
Product Name	Ethyl 2-(3-Cyano-6-Fluoro-2-(Trifluoromethyl)Quinolin-4-Yl)Acetate
CAS No.	1260811-87-7
Molecular Formula	C₁₅H₁₀F₄N₂O₂
Molecular Weight	326.25 g/mol
Synonyms	4-Quinolineacetic acid, 3-cyano-6-fluoro-2-(trifluoromethyl)-, ethyl ester; Ethyl 3-cyano-6-fluoro-2-(trifluoromethyl)-4-quinolineacetate; 1260811-87-7; Ethyl (3-cyano-6-fluoro-2-trifluoromethylquinolin-4-yl)acetate; 2-(3-Cyano-6-fluoro-2-(trifluoromethyl)quinolin-4-yl)acetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-(3-Cyano-6-Fluoro-2-(trifluoromethyl)quinolin-4-yl)acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.