Description

Benzyl 4-Amino-5,6,8,9-Tetrahydropyrimido[4,5-D]Azepine-7-Carboxylate CAS NO 1260810-71-6 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the synthesis of innovative therapeutic agents.

Application

This specialized intermediate is designed for sophisticated chemical synthesis in regulated environments. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• API Development: Serves as a core scaffold for constructing complex molecules in active pharmaceutical ingredient (API) manufacturing processes.
• Contract Synthesis: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under GMP or non-GMP conditions.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical and pharmacological assays.

Basic Information

Product Name	Benzyl 4-Amino-5,6,8,9-Tetrahydropyrimido[4,5-D]Azepine-7-Carboxylate
CAS No.	1260810-71-6
Molecular Formula	C17H18N4O2
Molecular Weight	310.35 g/mol
Synonyms	Benzyl 4-aminotetrahydropyrimidoazepine-7-carboxylate; 7-Benzyloxycarbonyl-4-amino-5,6,8,9-tetrahydropyrimido[4,5-d]azepine; 4-Amino-5,6,8,9-tetrahydro-7H-pyrimido[4,5-d]azepine-7-carboxylic acid benzyl ester; UNII-7K3Q4X8T7I; 1260810-71-6; Benzyl 4-amino-5,6,8,9-tetrahydropyrimido[4,5-d]azepine-7-carboxylate; 7H-Pyrimido[4,5-d]azepine-7-carboxylic acid, 4-amino-5,6,8,9-tetrahydro-, phenylmethyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research and development. Certificates of Analysis (COA) are provided with each shipment, detailing purity, identity, and impurity profiles. Quality is verified through modern analytical techniques including HPLC, GC, NMR, and mass spectrometry. We support development under quality systems appropriate for your project stage, from research-grade to cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.