Description

6-Bromo-1,2,3,4-Tetrahydro-Naphthalene-2-Carboxylic Acid is a high-purity, versatile brominated tetralin carboxylic acid derivative that serves as a critical synthetic intermediate. Its value lies in providing a functionalized, conformationally constrained scaffold for constructing complex molecular architectures in advanced research and development. This compound is essential for medicinal chemists and process development scientists working in pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its bromine atom for further functionalization.
• Ligand and Catalyst Synthesis: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Intermediate for creating specialty polymers, liquid crystals, and organic electronic materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis services, supporting scale-up from milligram to kilogram quantities for clinical trials.

Basic Information

Product Name	6-Bromo-1,2,3,4-Tetrahydro-Naphthalene-2-Carboxylic Acid
CAS No.	1260803-17-5
Molecular Formula	C11H11BrO2
Molecular Weight	255.11 g/mol
Synonyms	6-Bromo-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid; 2-Naphthalenecarboxylic acid, 6-bromo-1,2,3,4-tetrahydro-; 6-Bromotetralin-2-carboxylic Acid; 2-Carboxy-6-bromotetralin; 6-Bromo-3,4-dihydro-2-naphthoic acid; 6-Bromo-1,2,3,4-tetrahydro-2-naphthoic acid; 6-Bromo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-1,2,3,4-Tetrahydro-Naphthalene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.