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6-Bromo-4-Chloro-3-Iodoquinoline CAS NO 1260787-47-0
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CAS No.:1260787-47-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-Bromo-4-Chloro-3-Iodoquinoline is a high-purity, multi-halogenated quinoline derivative, a crucial advanced intermediate in modern organic synthesis. Its distinct halogen substitution pattern makes it a valuable scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists in the life sciences sector for applications in drug discovery and the synthesis of functional materials.
Application
- Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research programs.
- Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated quinoline core.
- Material Science Precursor: Serves as a starting material for creating organic electronic materials, ligands for catalysis, and specialty dyes.
- Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the presence of bromo and iodo substituents.
- Chemical Library Synthesis: Employed in combinatorial and parallel synthesis to generate diverse compound libraries for high-throughput screening.
- Academic Research: Used in universities and research institutes for methodological studies in heterocyclic and organohalogen chemistry.
Basic Information
| Item | Details |
|---|---|
| Product Name | 6-Bromo-4-Chloro-3-Iodoquinoline |
| CAS No. | 1260787-47-0 |
| Molecular Formula | C9H4BrClIN |
| Molecular Weight | 368.40 g/mol |
| Synonyms | 6-Bromo-4-chloro-3-iodoquinoline; 4-Chloro-6-bromo-3-iodoquinoline; 3-Iodo-6-bromo-4-chloroquinoline; Quinoline, 6-bromo-4-chloro-3-iodo-; BCIQ; 1260787-47-0; 6-Br-4-Cl-3-I-quinoline |
| EINECS | Contact for details |
Quality Control
Every batch of 6-Bromo-4-Chloro-3-Iodoquinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to ensure batch-to-batch consistency and reliability for your critical synthetic applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or crystalline solid |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 97.0% |
| Melting Point | Contact for details |
| Heavy Metals | < 20 ppm |
| Residual Solvents (GC) | Complies with ICH guidelines |
| Water Content (KF) | < 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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