Description

5'-Bromospiro[Cyclopropane-1,3'-Indoline] is a high-value, spirocyclic organic building block featuring a bromine substituent on the indoline moiety. This compound is of significant interest for its unique three-dimensional structure and reactivity, which makes it a versatile intermediate in advanced synthetic chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its spirocyclic scaffold for enhanced biological activity and selectivity.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex molecular architectures via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other functional group transformations.
• Material Science Research: Investigated as a monomer or precursor for the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein-ligand interactions.

Basic Information

Product Name	5'-Bromospiro[Cyclopropane-1,3'-Indoline]
CAS No.	1260763-03-8
Molecular Formula	C10H8BrN
Molecular Weight	222.08 g/mol
Synonyms	5'-Bromo-1'H-spiro[cyclopropane-1,3'-indoline]; 5-Bromospiro[cyclopropane-1,3'-indoline]; 5'-Bromo-spiro(cyclopropane-1,3'-indoline); Spiro[cyclopropane-1,3'-indoline], 5'-bromo-; 1260763-03-8
EINECS	Contact for details

Quality Control

Our 5'-Bromospiro[Cyclopropane-1,3'-Indoline] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications in GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.