Description

5-Fluoro-3-Methylbenzodisoxazole is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique benzodisoxazole scaffold and fluorine substituent impart desirable biological and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated benzodisoxazole moiety.
• Material Science Research: Acts as a building block for creating specialty polymers, liquid crystals, or organic electronic materials due to its rigid, aromatic structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized fluorinated heterocycles.

Basic Information

Product Name	5-Fluoro-3-Methylbenzodisoxazole
CAS No.	1260762-27-3
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	5-Fluoro-3-methyl-1,2-benzisoxazole; 3-Methyl-5-fluorobenzisoxazole; 5-Fluoro-3-methylbenzo[d]isoxazole; 1,2-Benzisoxazole, 5-fluoro-3-methyl-; 5-Fluoro-3-methyl-2,1-benzisoxazole; 1260762-27-3; 5-Fluoro-3-methyl-1,2-benzisoxazole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-Methylbenzodisoxazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.