Description

5-Amino-3-Iodo-1H-Pyrazolo[3,4-B]Pyridine is a high-purity, heterocyclic organic compound featuring a fused pyrazolopyridine core functionalized with amino and iodo substituents. This specific molecular architecture makes it a valuable and versatile pharmaceutical intermediate and research chemical for advanced synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to construct complex molecules for drug discovery and specialty chemical applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic scaffold.
• Material Science Precursor: Acts as a starting material for creating organic electronic materials, ligands for catalysis, and advanced polymers.
• Chemical Biology Probe: Employed in medicinal chemistry and biochemical research to study protein-ligand interactions and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5-Amino-3-Iodo-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	1260681-83-1
Molecular Formula	C6H5IN4
Molecular Weight	260.03 g/mol
Synonyms	3-Iodo-1H-pyrazolo[3,4-b]pyridin-5-amine; 5-Amino-3-iodo-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 5-amino-3-iodo-; 5-Amino-3-iodopyrazolo[3,4-b]pyridine; 3-Iodo-1H-pyrazolo[3,4-b]pyridin-5-ylamine; CAS 1260681-83-1
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-3-Iodo-1H-Pyrazolo[3,4-B]Pyridine is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.