Description

7-Bromo-3-Chlorobenzo[D]Isoxazole is a high-purity halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Acts as a versatile handle for creating molecular probes to study enzyme function and biological pathways.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for sequential palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Heterocycle Functionalization: Used to introduce the benzoisoxazole moiety into larger molecular systems, modifying their physical and biological properties.

Basic Information

Product Name	7-Bromo-3-Chlorobenzo[D]Isoxazole
CAS No.	1260677-07-3
Molecular Formula	C7H3BrClNO
Molecular Weight	232.46 g/mol
Synonyms	3-Chloro-7-bromobenzo[d]isoxazole; 7-Bromo-3-chloro-1,2-benzisoxazole; Benzo[d]isoxazole, 7-bromo-3-chloro-; 1,2-Benzisoxazole, 7-bromo-3-chloro-; 1260677-07-3; 7-Bromo-3-chloro-benzo[d]isoxazole
EINECS	Contact for details

Quality Control

Our 7-Bromo-3-Chlorobenzo[D]Isoxazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.