Description

2,8-Dichloro-1,7-Naphthyridine is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, where its specific substitution pattern enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Acts as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the naphthyridine core into more complex molecular architectures.
• Academic & R&D: Essential for fundamental research in heterocyclic chemistry and for exploring new reaction pathways in organic chemistry laboratories.

Basic Information

Product Name	2,8-Dichloro-1,7-Naphthyridine
CAS No.	1260664-21-8
Molecular Formula	C8H4Cl2N2
Molecular Weight	199.04 g/mol
Synonyms	1,7-Naphthyridine, 2,8-dichloro-; 2,8-Dichloro-1,7-naphthyridine; 2,8-Dichloro-1,7-diazanaphthalene; 1,7-Diazanaphthalene, 2,8-dichloro-; Dichloro-1,7-naphthyridine
EINECS	Contact for details

Quality Control

Our 2,8-Dichloro-1,7-Naphthyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere or in a desiccator for long-term preservation to prevent moisture absorption. Ideal storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.