Description

3,4-Dihydro-2H-Benzo[1,4]Oxazine-3-Carboxylic Acid is a high-value heterocyclic building block and key synthetic intermediate in advanced organic chemistry. This compound matters for its crucial role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science. Its defined structure offers a versatile scaffold for further functionalization.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in the research and synthesis of new generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Synthesis: Acts as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Utilized in the development of advanced organic materials, including polymers and liquid crystals with specific electronic properties.
• Academic & Institutional Research: A valuable reagent for universities and R&D institutes exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	3,4-Dihydro-2H-Benzo[1,4]Oxazine-3-Carboxylic Acid
CAS No.	1260643-24-0
Molecular Formula	C9H9NO3
Molecular Weight	179.17 g/mol
Synonyms	2H-1,4-Benzoxazine-3-carboxylic acid, 3,4-dihydro-; 3-Carboxy-3,4-dihydro-2H-1,4-benzoxazine; 3,4-Dihydro-2H-1,4-benzoxazine-3-carboxylic acid; Benzo[1,4]oxazine-3-carboxylic acid, 3,4-dihydro-2H-; 1260643-24-0; 3,4-Dihydro-2H-benzo[b][1,4]oxazine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-2H-Benzo[1,4]Oxazine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.