Description

6-Fluoro-4-Hydroxy-2-(Trifluoromethyl)Quinoline-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring both fluorine and trifluoromethyl groups, makes it a critical intermediate for developing novel compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobial agents, and other small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for creating new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the fluorine substituents.
• Material Science: Used in the research and development of advanced organic electronic materials, such as OLEDs or semiconductors, due to its electron-deficient quinoline core.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization in medicinal and combinatorial chemistry to create diverse chemical libraries for screening.
• Fluorinated Compound Development: Essential for researchers specializing in organofluorine chemistry, aiming to incorporate trifluoromethyl and fluoro groups into complex molecules.

Basic Information

Product Name	6-Fluoro-4-Hydroxy-2-(Trifluoromethyl)Quinoline-3-Carbonitrile
CAS No.	1260642-28-1
Molecular Formula	C₁₁H₄F₄N₂O
Molecular Weight	256.16 g/mol
Synonyms	6-Fluoro-4-hydroxy-2-(trifluoromethyl)quinoline-3-carbonitrile; 2-(Trifluoromethyl)-6-fluoro-4-hydroxy-3-quinolinecarbonitrile; 4-Hydroxy-6-fluoro-2-(trifluoromethyl)quinoline-3-carbonitrile; 6-Fluoro-4-hydroxy-2-trifluoromethylquinoline-3-carbonitrile; 3-Cyano-6-fluoro-4-hydroxy-2-(trifluoromethyl)quinoline; Quinoline-3-carbonitrile, 6-fluoro-4-hydroxy-2-(trifluoromethyl)-; CAS 1260642-28-1
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Hydroxy-2-(Trifluoromethyl)Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.