Description

(2S,4S)-4-Amino-1-(tert-Butoxycarbonyl)Piperidine-2-Carboxylic Acid is a high-purity, stereochemically defined piperidine derivative that serves as a critical chiral building block in modern synthetic chemistry. Its value lies in providing a rigid, functionalized scaffold essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting the central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially protease inhibitors and other small molecule therapeutics.
• Peptidomimetic Research: Used to introduce constrained, non-natural amino acid motifs into peptide backbones to enhance stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high stereochemical purity.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(2S,4S)-4-Amino-1-(tert-Butoxycarbonyl)Piperidine-2-Carboxylic Acid
CAS No.	1260592-54-8
Molecular Formula	C11H20N2O4
Molecular Weight	244.29 g/mol
Synonyms	1-Boc-4-amino-(2S,4S)-piperidine-2-carboxylic acid; (2S,4S)-1-(tert-Butoxycarbonyl)-4-aminopiperidine-2-carboxylic acid; (2S,4S)-4-Amino-1-Boc-piperidine-2-carboxylic acid; Boc-4-Amino-(2S,4S)-piperidine-2-COOH; (2S,4S)-1-N-Boc-4-aminopiperidine-2-carboxylic acid; tert-Butyl (2S,4S)-4-amino-2-carboxypiperidine-1-carboxylate; (S,S)-Boc-4-Amino-pipecolic acid
EINECS	Contact for details

Quality Control

Our (2S,4S)-4-Amino-1-(tert-Butoxycarbonyl)Piperidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for advanced research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.