Description

6,8-Dichloro-3,4-Dihydronaphthalen-1(2H)-One is a high-value, halogenated tetralone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique chlorinated structure makes it an essential building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for its role in facilitating key synthetic transformations.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Building block for developing advanced herbicides and fungicides with specific chlorinated aromatic backbones.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and other functional materials due to its rigid, substituted naphthalene core.
• Chemical Synthesis: Versatile intermediate for Suzuki-Miyaura and other cross-coupling reactions to create complex polycyclic structures.
• Academic & Industrial R&D: Serves as a standard or starting material in methodological studies and scale-up process optimization within contract research organizations (CROs) and fine chemical manufacturers.

Basic Information

Product Name	6,8-Dichloro-3,4-Dihydronaphthalen-1(2H)-One
CAS No.	1260017-53-5
Molecular Formula	C10H8Cl2O
Molecular Weight	215.08 g/mol
Synonyms	6,8-Dichloro-3,4-dihydro-1(2H)-naphthalenone; 6,8-Dichloro-1-tetralone; 6,8-Dichloro-3,4-dihydronaphthalen-1-one; 1(2H)-Naphthalenone, 6,8-dichloro-3,4-dihydro-; 6,8-Dichloro-α-tetralone; 6,8-Dichloro-1-oxo-1,2,3,4-tetrahydronaphthalene
EINECS	Contact for details

Quality Control

Our production of 6,8-Dichloro-3,4-Dihydronaphthalen-1(2H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All material is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.