Description

6-Bromo-5-Fluoro-2,3,4-Trihydronaphthalen-1-One is a high-value, multi-functional halogenated naphthalenone derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its halogenated aromatic structure.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and functional group transformations to create diverse chemical libraries.
• Material Science Precursor: Acts as a starting material for synthesizing specialized organic electronic materials and liquid crystals.
• Academic & Industrial R&D: Essential for methodological studies in fluorination and bromination chemistry and for exploring new reaction pathways.

Basic Information

Product Name	6-Bromo-5-Fluoro-2,3,4-Trihydronaphthalen-1-One
CAS No.	1260013-62-4
Molecular Formula	C10H8BrFO
Molecular Weight	243.07 g/mol
Synonyms	6-Bromo-5-fluoro-1-tetralone; 5-Fluoro-6-bromo-3,4-dihydronaphthalen-1(2H)-one; 1(2H)-Naphthalenone, 6-bromo-5-fluoro-3,4-dihydro-; 6-Bromo-5-fluoro-α-tetralone; 6-Bromo-5-fluoro-3,4-dihydro-1(2H)-naphthalenone; 5-Fluoro-6-bromo-α-tetralone; 6-Bromo-5-fluoro-1-oxo-1,2,3,4-tetrahydronaphthalene
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Fluoro-2,3,4-Trihydronaphthalen-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.