Description

4-Methyl-3-(trifluoromethyl)-DL-phenylalanine, 97% is a non-natural, fluorinated amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the unique combination of the phenylalanine backbone with a trifluoromethyl group, which can dramatically alter the physicochemical and metabolic properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients, peptide mimetics, and molecular probes where fluorine substitution is strategically employed.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders, metabolic diseases, and oncology.
• Peptidomimetics & Bioactive Peptides: Used to incorporate fluorinated aromatic side chains into peptide sequences to enhance stability, lipophilicity, and binding affinity.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and plant growth regulators, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and isotopic labels for studying enzyme mechanisms and protein interactions.
• Material Science: A potential monomer or modifier for specialty polymers and advanced materials requiring specific fluorine-containing motifs.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in asymmetric synthesis, fluorination chemistry, and amino acid derivative synthesis.

Basic Information

Product Name	4-Methyl-3-(Trifluoromethyl)-DL-Phenylalanine, 97%
CAS No.	1259992-37-4
Molecular Formula	C11H12F3NO2
Molecular Weight	247.21 g/mol
Synonyms	DL-4-Methyl-3-(trifluoromethyl)phenylalanine; 2-Amino-3-[4-methyl-3-(trifluoromethyl)phenyl]propanoic acid; 3-(4-Methyl-3-(trifluoromethyl)phenyl)alanine; (±)-4-Methyl-3-(trifluoromethyl)phenylalanine; 4-Methyl-3-trifluoromethyl-DL-phenylalanine; α-Amino-4-methyl-3-(trifluoromethyl)benzenepropanoic acid; (RS)-3-(4-Methyl-3-(trifluoromethyl)phenyl)alanine
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-(trifluoromethyl)-DL-phenylalanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the specified 97% purity grade. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We adhere to cGMP principles for the manufacture of advanced pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if possible to maintain long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.