Description

1(2H)-Quinolinecarboxylic Acid, 3-(Acetylamino)-3,4-Dihydro-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex quinoline-based structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders or infectious diseases.
• Organic Synthesis Building Block: Used in research laboratories for constructing novel quinoline and dihydroquinoline derivatives with potential biological activity.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of candidate drugs.
• Process Chemistry Development: Employed in scaling up synthetic routes from milligram to kilogram scale for preclinical and clinical trial material production.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals where a high degree of molecular complexity and purity is required.

Basic Information

Product Name	1(2H)-Quinolinecarboxylic Acid, 3-(Acetylamino)-3,4-Dihydro-, 1,1-Dimethylethyl Ester
CAS No.	1259224-07-1
Molecular Formula	C16H20N2O3
Molecular Weight	288.34 g/mol
Synonyms	tert-Butyl 3-acetamido-3,4-dihydro-1H-quinoline-1-carboxylate; 3-(Acetylamino)-3,4-dihydro-1(2H)-quinolinecarboxylic Acid 1,1-Dimethylethyl Ester; 3-Acetamido-3,4-dihydroquinoline-1(2H)-carboxylic Acid tert-Butyl Ester; tert-Butyl 3-acetylamino-1,2,3,4-tetrahydroquinoline-1-carboxylate; 1,1-Dimethylethyl 3-(Acetylamino)-3,4-dihydro-1(2H)-quinolinecarboxylate; 3-Acetamidotetrahydroquinoline-1-carboxylic Acid tert-Butyl Ester; Boc-Protected 3-Acetamidotetrahydroquinoline
EINECS	Contact for details

Quality Control

Our production of 1(2H)-Quinolinecarboxylic Acid, 3-(Acetylamino)-3,4-Dihydro-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed when not in use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.