Description

1H-Pyrrolo[2,3-C]Pyridine-4-Carboximidamide, n-Hydroxy- is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic carboximidamide class. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in the development of assay probes and inhibitors for studying specific enzymatic or cellular processes in life science research.
• Contract Development and Manufacturing (CDMO): Supplied to CDMOs for scale-up synthesis under cGMP conditions for clinical trial material and commercial API production.

Basic Information

Product Name	1H-Pyrrolo[2,3-C]Pyridine-4-Carboximidamide, n-Hydroxy-
CAS No.	1258875-13-6
Molecular Formula	C8H9N5O
Molecular Weight	191.19 g/mol
Synonyms	N-Hydroxy-1H-pyrrolo[2,3-c]pyridine-4-carboximidamide; 4-(Hydroxycarbamimidoyl)-1H-pyrrolo[2,3-c]pyridine; 1H-Pyrrolo[2,3-c]pyridine-4-carboximidamide, N-hydroxy-; 1258875-13-6; 4-Carbamimidoyl-1H-pyrrolo[2,3-c]pyridin-1-ol (tautomer); Hydroxypyrrolopyridinecarboximidamide
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-C]Pyridine-4-Carboximidamide, n-Hydroxy- adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques (including HPLC, NMR, and MS) to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting regulatory filings and quality assurance in cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.