Description

4-Hydroxy-1-(6-Quinolinylcarbonyl)-4-Piperidineacetaldehyde CAS NO 1258652-76-4 is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or other complex biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.
• Biochemical Research: May be utilized in the development of enzyme inhibitors or receptor modulators due to its specific quinoline and piperidine motifs.
• Custom Synthesis: An essential component for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services to the biopharma industry.

Basic Information

Product Name	4-Hydroxy-1-(6-Quinolinylcarbonyl)-4-Piperidineacetaldehyde
CAS No.	1258652-76-4
Molecular Formula	C₁₇H₁₈N₂O₃
Molecular Weight	298.34 g/mol
Synonyms	4-Hydroxy-1-(quinoline-6-carbonyl)piperidine-4-acetaldehyde; 4-Piperidineacetaldehyde, 4-hydroxy-1-(6-quinolinylcarbonyl)-; 1-(6-Quinolinecarbonyl)-4-hydroxy-4-piperidineacetaldehyde; 4-Hydroxy-1-(6-quinolylcarbonyl)-4-piperidineacetaldehyde; 4-Hydroxy-1-(quinolin-6-ylcarbonyl)piperidine-4-acetaldehyde; 4-Hydroxy-1-[(6-quinolinyl)carbonyl]-4-piperidineacetaldehyde
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-1-(6-Quinolinylcarbonyl)-4-Piperidineacetaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.