Description

(6,7,8,9-Tetrahydro-5H-[1,2,4]Triazolo[4,3-A]Azepin-3-Ylmethyl)Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1258650-58-6. This compound is a key synthetic building block valued for its fused triazoloazepine core, which is integral to the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates targeting specific receptors.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs for novel small molecules.
• CNS Drug Discovery: Its structural motif is relevant for developing compounds aimed at neurological and psychiatric conditions.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study biological pathways and enzyme functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	(6,7,8,9-Tetrahydro-5H-[1,2,4]Triazolo[4,3-A]Azepin-3-Ylmethyl)Amine Hydrochloride
CAS No.	1258650-58-6
Molecular Formula	C9H15ClN4
Molecular Weight	214.70 g/mol
Synonyms	1-(6,7,8,9-Tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)methanamine hydrochloride; 3-(Aminomethyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine hydrochloride; (6,7,8,9-Tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)methanamine hydrochloride; 5H-[1,2,4]Triazolo[4,3-a]azepin-3-methanamine, 6,7,8,9-tetrahydro-, hydrochloride; Triazoloazepine amine hydrochloride; CAS 1258650-58-6
EINECS	Contact for details

Quality Control

Our (6,7,8,9-Tetrahydro-5H-[1,2,4]Triazolo[4,3-A]Azepin-3-Ylmethyl)Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.