Description

1'-Boc-1,2-Dihydro-6-Methoxy-2-Oxo-Spiro[3H-Indole-3,4'-Piperidine] is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic indole-piperidine scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with potential neurological and oncological applications. It is primarily needed by R&D scientists and process chemists in pharmaceutical, biotechnology, and fine chemical industries for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex small-molecule drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Used in the construction of bifunctional molecules designed for targeted protein degradation.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	1'-Boc-1,2-Dihydro-6-Methoxy-2-Oxo-Spiro[3H-Indole-3,4'-Piperidine]
CAS No.	1258639-06-3
Molecular Formula	C19H24N2O4
Molecular Weight	344.41 g/mol
Synonyms	1,2-Dihydro-6-methoxy-2-oxospiro[3H-indole-3,4'-piperidine]-1'-carboxylic acid tert-butyl ester; tert-Butyl 6-methoxy-2-oxo-1,2-dihydrospiro[indole-3,4'-piperidine]-1'-carboxylate; 1'-Boc-6-methoxy-2-oxospiro[indoline-3,4'-piperidine]; Spiro[indoline-3,4'-piperidine]-1'-carboxylic acid tert-butyl ester, 6-methoxy-2-oxo-; 1'-Boc-6-methoxy-2-oxospiro[indole-3,4'-piperidine]; 1258639-06-3; BOC-protected spirocyclic indole piperidine.
EINECS	Contact for details

Quality Control

Our 1'-Boc-1,2-Dihydro-6-Methoxy-2-Oxo-Spiro[3H-Indole-3,4'-Piperidine] is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural integrity suitable for demanding pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.