Description

5-Formyl-Benzofuran-2-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both an aldehyde and a nitrile group on a benzofuran core, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the benzofuran scaffold is valued for its bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or building blocks for conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent tags, photoaffinity labels, and other molecular probes for biological studies.
• Academic & Contract Research: An essential reagent for methodology development and exploratory synthesis in university and CRO laboratories.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and fragrances.

Basic Information

Product Name	5-Formyl-Benzofuran-2-Carbonitrile
CAS No.	1258154-58-3
Molecular Formula	C10H5NO2
Molecular Weight	171.15 g/mol
Synonyms	2-Cyano-5-formylbenzofuran; 5-Formyl-2-benzofurancarbonitrile; Benzofuran-2-carbonitrile, 5-formyl-; 2-Benzofurancarbonitrile, 5-formyl-; 5-Formylbenzo[b]furan-2-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 5-Formyl-Benzofuran-2-Carbonitrile is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its property of being easily oxidized, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.