Description

p-[2-Oxo-1-(Phenylmethoxy)Propyl]Phosphonic Acid Dimethyl Ester is a specialized organophosphorus compound that serves as a critical intermediate in advanced organic synthesis. Its unique structure, featuring both a phosphonate ester and a protected keto-alcohol moiety, makes it a valuable building block for constructing complex molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection agent discovery. Its controlled reactivity profile enables precise synthetic transformations, facilitating the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for molecules requiring phosphonate or phosphate ester functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators where the phosphonate group is integral to biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized phosphonate-based ligands used in asymmetric catalysis and metal complexation.
• Material Science Research: Employed in the development of novel polymers, flame retardants, or surface-modifying agents due to its organophosphorus core.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms, particularly those involving phosphorylation or phosphonate metabolism.

Basic Information

Product Name	p-[2-Oxo-1-(Phenylmethoxy)Propyl]Phosphonic Acid Dimethyl Ester
CAS No.	1258067-56-9
Molecular Formula	C13H19O5P
Molecular Weight	286.26 g/mol
Synonyms	Dimethyl (4-{2-oxo-1-[(phenylmethoxy)methyl]propyl}phenyl)phosphonate; 4-[2-Oxo-1-(phenylmethoxy)propyl]phenylphosphonic Acid Dimethyl Ester; Phosphonic Acid, P-[2-Oxo-1-(Phenylmethoxy)Propyl]-, Dimethyl Ester; Benzyl 1-(4-(Dimethoxyphosphoryl)phenyl)-2-oxopropyl Ether
EINECS	Contact for details

Quality Control

Our production of p-[2-Oxo-1-(Phenylmethoxy)Propyl]Phosphonic Acid Dimethyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.