Description

3-Acetyl-6-Fluoro-4-(4-Fluorophenyl)Quinolin-2(1H)-One is a high-purity fluorinated quinolinone derivative, serving as a critical advanced pharmaceutical intermediate. Its molecular structure, featuring acetyl and fluorophenyl substituents, makes it a valuable building block for synthesizing novel bioactive compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new drug candidates with optimized properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorinated quinolinone core can contribute to enhanced biological activity and environmental stability.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways in academic and industrial research settings.
• Material Science: Investigated as a monomer or additive for creating specialty polymers and organic electronic materials due to its conjugated system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	3-Acetyl-6-Fluoro-4-(4-Fluorophenyl)Quinolin-2(1H)-One
CAS No.	1257535-68-4
Molecular Formula	C₁₇H₁₁F₂NO₂
Molecular Weight	299.27 g/mol
Synonyms	3-Acetyl-6-fluoro-4-(4-fluorophenyl)-1,2-dihydroquinolin-2-one; 3-Acetyl-6-fluoro-4-(4-fluorophenyl)-2(1H)-quinolinone; 4-(4-Fluorophenyl)-3-acetyl-6-fluoro-1H-quinolin-2-one; 2(1H)-Quinolinone, 3-acetyl-6-fluoro-4-(4-fluorophenyl)-; 1257535-68-4; 3-Acetyl-6-fluoro-4-(p-fluorophenyl)quinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 3-Acetyl-6-Fluoro-4-(4-Fluorophenyl)Quinolin-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.