Description

2-Bromo-6-Cyano-3-Fluorophenol is a high-purity, multi-functional halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring bromo, cyano, and fluoro substituents on a phenolic core, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the halogen and cyano groups contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science applications.
• Functional Material Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers due to its electron-withdrawing substituents.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Bromo-6-Cyano-3-Fluorophenol
CAS No.	1257535-02-6
Molecular Formula	C7H3BrFNO
Molecular Weight	216.01 g/mol
Synonyms	3-Fluoro-2-bromo-6-hydroxybenzonitrile; 2-Bromo-6-cyano-3-fluorophenol; 6-Cyano-3-fluoro-2-bromophenol; Phenol, 2-bromo-6-cyano-3-fluoro-; 2-Bromo-3-fluoro-6-hydroxybenzonitrile; 3-Fluoro-6-hydroxy-2-bromobenzonitrile; 2-Bromo-3-fluorophenol-6-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-Cyano-3-Fluorophenol is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, GC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.