Description

(N)-1-(2-Nitrophenyl)Ethylcarboxy-(S)-3,4-Dicarboxyphenylglycine is a specialized chiral glycine derivative, serving as a high-value synthetic intermediate and ligand in advanced chemical synthesis. Its molecular architecture, featuring multiple carboxyl groups and a nitrophenyl moiety, makes it a critical component for constructing complex molecules with precise stereochemistry. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in asymmetric catalysis, peptide mimetic design, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in protease inhibitor and receptor antagonist research.
• Asymmetric Catalysis: Acts as a precursor or ligand for chiral catalysts used in enantioselective synthesis, crucial for producing single-isomer compounds.
• Peptidomimetic Chemistry: Used to introduce constrained, non-natural amino acid motifs into peptide analogs to enhance stability and biological activity.
• Chemical Biology Probes: Employed in the development of activity-based probes and molecular tools for studying enzyme function and protein interactions.
• Material Science Research: Serves as a functional monomer or cross-linker in the development of specialized polymers with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry projects.

Basic Information

Product Name	(N)-1-(2-Nitrophenyl)Ethylcarboxy-(S)-3,4-Dicarboxyphenylglycine
CAS No.	1257323-85-5
Molecular Formula	C19H16N2O9
Molecular Weight	416.34 g/mol
Synonyms	(S)-2-((((1-(2-Nitrophenyl)ethoxy)carbonyl)amino)-2-(3,4-dicarboxyphenyl)acetic acid; (S)-3,4-Dicarboxyphenylglycine, N-[(1-(2-nitrophenyl)ethoxy)carbonyl]-; N-[(1-(2-Nitrophenyl)ethoxy)carbonyl]-3,4-dicarboxy-L-phenylglycine; Nde-3,4-diCOOH-Phe-gly-OH (nitrophenyl ethyl ester protected); Chiral Nitrophenyl-Protected Dicarboxy Phenylglycine Derivative; CAS 1257323-85-5
EINECS	Contact for details

Quality Control

Every batch of (N)-1-(2-Nitrophenyl)Ethylcarboxy-(S)-3,4-Dicarboxyphenylglycine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee (S-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.