Description

1-(Azetidin-3-Yl)-3-Methylazetidin-3-Ol Di-Trifluoroacetate is a high-purity, advanced pharmaceutical intermediate featuring a unique azetidine-based scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting central nervous system and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of innovative drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting GPCRs (G-protein-coupled receptors).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its constrained azetidine ring system.
• Chemical Biology Probes: Serves as a precursor for developing tool compounds and molecular probes to study biological pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex nitrogen-containing heterocycles.
• Preclinical Development: Supplied in development quantities for the preparation of non-GMP and GMP batches for toxicology and early-phase clinical studies.

Basic Information

Product Name	1-(Azetidin-3-Yl)-3-Methylazetidin-3-Ol Di-Trifluoroacetate
CAS No.	1257294-12-4
Molecular Formula	C11H16F6N2O5
Molecular Weight	370.25 g/mol
Synonyms	3-Methyl-1-(3-azetidinyl)-3-azetidinol ditrifluoroacetate; 1-(Azetidin-3-yl)-3-methylazetidin-3-ol bis(trifluoroacetate); 3-Azetidinol, 1-(3-azetidinyl)-3-methyl-, bis(2,2,2-trifluoroacetate); 1-(3-Azetidinyl)-3-methyl-3-azetidinol Di-Trifluoroacetate; Azetidine-3-carboxylic acid derivative; 1257294-12-4
EINECS	Contact for details

Quality Control

Our 1-(Azetidin-3-Yl)-3-Methylazetidin-3-Ol Di-Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specified parameters. We support development with research-grade material and can scale production under cGMP guidelines for advanced clinical phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.