Description

2-Chloromethyl-7-Methoxy-1H-Quinazolin-4-One is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core quinazolinone scaffold, functionalized with reactive chloromethyl and methoxy groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition, anticancer, and anti-inflammatory activities.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactive quinazolinone core.
• Organic Synthesis Building Block: Serves as a versatile scaffold for medicinal chemistry, enabling the introduction of diverse substituents via the reactive chloromethyl group.
• Material Science Research: Investigated as a monomer or precursor for creating specialty polymers and advanced organic materials with specific electronic or photophysical properties.
• Academic & Contract Research: Essential for chemical research in universities and CROs (Contract Research Organizations) focused on heterocyclic chemistry and new synthetic methodologies.

Basic Information

Product Name	2-Chloromethyl-7-Methoxy-1H-Quinazolin-4-One
CAS No.	1257043-54-1
Molecular Formula	C₁₀H₉ClN₂O₂
Molecular Weight	224.64 g/mol
Synonyms	7-Methoxy-2-(chloromethyl)quinazolin-4(1H)-one; 2-(Chloromethyl)-7-methoxy-4(1H)-quinazolinone; 4(1H)-Quinazolinone, 2-(chloromethyl)-7-methoxy-; 2-Chloromethyl-7-methoxyquinazolin-4(1H)-one; 7-Methoxy-2-chloromethyl-1H-quinazolin-4-one; 2-Chloromethyl-7-methoxy-4(1H)-quinazolinone; 2-(Chloromethyl)-7-methoxy-1H-quinazolin-4-one
EINECS	Contact for details

Quality Control

Every batch of 2-Chloromethyl-7-Methoxy-1H-Quinazolin-4-One is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and ensure the product meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.