Description

(S)-2-Amino-2-(p-Tolyl)Ethanol Hydrochloride CAS NO 1256974-17-0 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry and functional groups make it a valuable precursor for the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel, optically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used to develop and synthesize chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating optically active herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and medicinal chemistry research programs.
• Peptidomimetic Chemistry: Used in the design and synthesis of peptide analogs and conformationally constrained bioactive molecules.

Basic Information

Product Name	(S)-2-Amino-2-(p-Tolyl)Ethanol Hydrochloride
CAS No.	1256974-17-0
Molecular Formula	C9H14ClNO
Molecular Weight	187.67 g/mol
Synonyms	(S)-2-Amino-2-(4-methylphenyl)ethanol hydrochloride; (S)-2-Amino-2-(p-tolyl)ethan-1-ol hydrochloride; (1S)-2-Amino-1-(4-methylphenyl)ethanol hydrochloride; (S)-(-)-2-Amino-2-(p-tolyl)ethanol HCl; (S)-2-Amino-1-(4-methylphenyl)ethanol hydrochloride; p-Tolylglycinol hydrochloride, (S)-; (S)-2-Amino-2-(4-tolyl)ethanol hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-2-(p-Tolyl)Ethanol Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with high-purity standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), chiral excess, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.