Description

6-Bromo-1-(Trifluoromethyl)Isoquinoline is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its unique molecular architecture, combining a brominated isoquinoline core with a trifluoromethyl group, which is critical for modulating the physicochemical and biological properties of target molecules. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for the creation of novel active ingredients and functional materials. CAS No. 1256836-88-0.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research due to its distinct halogen and fluorine atoms.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex molecular frameworks.
• Fluorine Chemistry Library Synthesis: An essential component for constructing diverse compound libraries focused on fluorine-containing molecules for high-throughput screening.

Basic Information

Product Name	6-Bromo-1-(Trifluoromethyl)Isoquinoline
CAS No.	1256836-88-0
Molecular Formula	C₁₀H₅BrF₃N
Molecular Weight	276.05 g/mol
Synonyms	6-Bromo-1-(trifluoromethyl)isoquinoline; 1-(Trifluoromethyl)-6-bromoisoquinoline; 6-Bromo-1-trifluoromethylisoquinoline; Isoquinoline, 6-bromo-1-(trifluoromethyl)-; 1256836-88-0; 6-Bromo-1-(trifluoromethyl)isoquinoline CAS 1256836-88-0
EINECS	Contact for details

Quality Control

Our 6-Bromo-1-(Trifluoromethyl)Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.