Description

3-Bromo-7,7-Dimethyl-7,8-Dihydroquinolin-5(6H)-One is a high-value, synthetically versatile brominated heterocyclic building block. This compound matters for its role as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce specific bromine functionality into quinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Research: Used in developing new candidates for herbicides, fungicides, and insecticides, where the quinoline core provides a bioactive framework.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or light-emitting compounds.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and biological pathways due to its modifiable bromine handle.
• Custom Synthesis and Contract Manufacturing: A key building block for custom synthesis houses serving the biotechnology and pharmaceutical industries.

Basic Information

Product Name	3-Bromo-7,7-Dimethyl-7,8-Dihydroquinolin-5(6H)-One
CAS No.	1256821-53-0
Molecular Formula	C₁₁H₁₂BrNO
Molecular Weight	254.12 g/mol
Synonyms	3-Bromo-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-one; 5(6H)-Quinolinone, 3-bromo-7,7-dimethyl-7,8-dihydro-; 3-Bromo-7,7-dimethyl-7,8-dihydroquinolin-5-one; 3-Bromo-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-one; 3-Bromo-7,7-dimethyl-1,2,3,4-tetrahydroquinolin-5-one (tautomer); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-7,7-Dimethyl-7,8-Dihydroquinolin-5(6H)-One is produced under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.