Description

6-Chloro-1,2,3,4-Tetrahydro-1,5-Naphthyridine is a high-value, synthetically versatile heterocyclic building block. This compound is critical for medicinal chemistry research and development, serving as a key intermediate in the synthesis of novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Kinase Inhibitor Development: Serves as a building block for potential kinase inhibitors, a major class of therapeutics in oncology.
• CNS Drug Candidate Synthesis: Employed in the research and development of novel compounds for neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	6-Chloro-1,2,3,4-Tetrahydro-1,5-Naphthyridine
CAS No.	1256811-30-9
Molecular Formula	C8H9ClN2
Molecular Weight	168.62 g/mol
Synonyms	6-Chloro-1,2,3,4-tetrahydro-1,5-naphthyridine; 1,2,3,4-Tetrahydro-6-chloro-1,5-naphthyridine; 6-Chloro-1,5-naphthyridine, 1,2,3,4-tetrahydro-; 6-Chloro-1,2,3,4-tetrahydro[1,5]naphthyridine; 1256811-30-9; 6-Chloro-1,5-naphthyridine tetrahydro derivative
EINECS	Contact for details

Quality Control

Our 6-Chloro-1,2,3,4-Tetrahydro-1,5-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.