Description

4-Bromo-2-Fluoropyridine-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. Its unique halogenated pyridine structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis in drug discovery.

Basic Information

Product Name	4-Bromo-2-Fluoropyridine-3-Carboxylic Acid
CAS No.	1256790-84-7
Molecular Formula	C6H3BrFNO2
Molecular Weight	220.00 g/mol
Synonyms	3-Pyridinecarboxylic acid, 4-bromo-2-fluoro-; 4-Bromo-2-fluoronicotinic acid; 2-Fluoro-4-bromopyridine-3-carboxylic acid; 4-Bromo-2-fluoro-3-pyridinecarboxylic acid; 4-Bromo-2-fluoropyridine-3-carboxylate; 1256790-84-7; 4-Br-2-F-3-PyCOOH
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Fluoropyridine-3-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for optimal long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.