Description

2-Methyl-3-(Piperidin-4-Yl)Pyridine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for medicinal chemistry research and the development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology applications. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring reliable, high-quality building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for CNS-targeting drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Preclinical Development: Serves as a critical material for producing compounds for pharmacological and toxicological evaluation.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting point for contract manufacturing organizations (CMOs) producing bespoke molecules for client projects.
• Academic Research: Employed in university and institutional labs for cutting-edge research in organic synthesis and drug discovery methodologies.

Basic Information

Item	Details
Product Name	2-Methyl-3-(Piperidin-4-Yl)Pyridine Dihydrochloride
CAS No.	1256787-95-7
Molecular Formula	C12H18N2·2HCl
Molecular Weight	263.21 g/mol (Free base: 190.29 g/mol)
Synonyms	2-Methyl-3-(4-piperidinyl)pyridine dihydrochloride; 3-(Piperidin-4-yl)-2-methylpyridine dihydrochloride; 2-Methyl-3-(piperidin-4-yl)pyridine hydrochloride (1:2); 2-Methyl-3-(4-piperidyl)pyridine dihydrochloride; 4-(2-Methyl-3-pyridyl)piperidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-(Piperidin-4-Yl)Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.